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filingDate 2016-07-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2018-10-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2018-10-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-106955275-B
titleOfInvention A kind of levo-oxiracetam spansule and preparation method thereof that stability is good
abstract A kind of levo-oxiracetam spansule that stability is good is made by following supplementary material:1 part of levo-oxiracetam, 1.1 parts ~ 1.7 parts of lactose, 1.5 parts ~ 2.2 parts of hypromellose K4M, 0.7 part ~ 1.5 parts of hypromellose K15M, 0.6 part ~ 1.1 parts of Brazil wax, 0.12 part ~ 0.20 part of octadecanol, 0.02 ~ 0.08 part of sodium thiosulfate, 2.8 parts ~ 3.5 parts of the ethanol solution that volume fraction is 50% ~ 70%;Levo-oxiracetam spansule of the present invention has release uniformity good, each time point release RSD is respectively less than 6% between different samples, rate of release is slow, deenergized period is up to 12 hours, meanwhile, this product stability is good, related substance only increases by 0.05% in shelf life, shelf life is up to 24 months, preparation process simple possible, is worth marketing.
priorityDate 2016-07-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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