http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106947107-B
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08J2325-06 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08F8-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08J9-36 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08F8-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08J9-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08F8-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08L25-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08F112-08 |
filingDate | 2017-03-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2019-08-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2019-08-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-106947107-B |
titleOfInvention | The preparation method of the superbranched polystyrene perforated membrane of adriamycin is grafted on hole wall |
abstract | The present invention relates to a kind of preparation methods for the superbranched polystyrene perforated membrane that adriamycin is grafted on hole wall, first, because dissaving polymer has the abundant end group that may modify convenient for improving the grafting amount of Doxorubicin molecules, secondly, perforated membrane pore structure abundant makes it have great specific surface area, not only it is conducive to be grafted upper more Doxorubicin molecules, but also is conducive to the release of adriamycin.Furthermore acylhydrazone key is introduced into polymer porous film drug delivery system, it is expected to realize the effect to the pH switch controlled release of anticancer drug.Meanwhile dynamic covalent bond is a kind of relatively more stable supermolecular mechanism, is directly connected to drug molecule by reversible acylhydrazone key, is expected to further increase stability, sensitivity and the controlling of polymer porous film drug delivery system.This polymer porous film is expected to be widely applied in fields such as drug delivery, bio-medical materials. |
priorityDate | 2017-03-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 93.