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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-65616
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-6561
filingDate 2017-04-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2020-01-07-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2020-01-07-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-106946935-B
titleOfInvention Preparation method of diastereoisomer nucleoside derivative
abstract The present invention relates to a process for the preparation of diastereoisomeric compound I, said process comprising the steps of: heating and stirring the compound III in an organic solvent to convert the configuration of the compound III to obtain a compound I, wherein the X group is halogen; compared with the prior artThe preparation method has the advantages of cheap and easily-obtained raw materials, mild reaction conditions, few side reactions, high yield, small environmental pollution and suitability for industrial production, and provides a new way for preparing the key intermediate of tenofovir alafenamide fumarate.
priorityDate 2017-04-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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Total number of triples: 36.