http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106946935-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-65616 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-6561 |
filingDate | 2017-04-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2020-01-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2020-01-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-106946935-B |
titleOfInvention | Preparation method of diastereoisomer nucleoside derivative |
abstract | The present invention relates to a process for the preparation of diastereoisomeric compound I, said process comprising the steps of: heating and stirring the compound III in an organic solvent to convert the configuration of the compound III to obtain a compound I, wherein the X group is halogen; compared with the prior artThe preparation method has the advantages of cheap and easily-obtained raw materials, mild reaction conditions, few side reactions, high yield, small environmental pollution and suitability for industrial production, and provides a new way for preparing the key intermediate of tenofovir alafenamide fumarate. |
priorityDate | 2017-04-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 36.