http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106943405-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-4866 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2054 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2059 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-496 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-496 |
| filingDate | 2016-01-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-04-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-04-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-106943405-B |
| titleOfInvention | Aripiprazole preparation and preparation method thereof |
| abstract | The invention belongs to the field of drug research and development, and particularly relates to an aripiprazole preparation and a preparation method thereof. The aripiprazole preparation comprises the following raw materials in parts by weight: 2.0-15.0 parts of aripiprazole; 60.0-90.0 parts of a filler; 1.0-18.0 parts of a solubilizer; 1.0-7.0 parts of a disintegrating agent; 0.5-6.0 parts of a lubricant. The aripiprazole preparation of the invention is directly prepared without granulation and drying, so the aripiprazole preparation does not contain binding agents such as water, ethanol, povidone, hydroxypropyl cellulose and other organic solvents, the generation of aripiprazole hydrate and the subsequent associated polymorphic transformation are greatly reduced, the quantity of related substances can be obviously reduced, the dissolution property and stability are good, the bioavailability is high, and the individual difference is small. |
| priorityDate | 2016-01-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 43.