http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106939297-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2500-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-117 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-105 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2523-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-11 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-113 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2533-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2500-84 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0693 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-067 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-09 |
| filingDate | 2017-02-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-08-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2020-08-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-106939297-B |
| titleOfInvention | Method for establishing liver cancer xenograft tumor model based on liver cancer circulating tumor cell bio-gel hanging drop culture method |
| abstract | The invention relates to the technical field of biological medicine, in particular to a method for constructing a xenograft tumor based on a temperature-sensitive biological gel hanging drop culture liver cancer circulating tumor system, which can amplify circulating tumor cells of a liver cancer patient in vitro and form a multicellular clone through the culture system, and the clone is selected to inoculate a nude mouse to form tumors under the skin, in the liver and in the lung to build a xenograft tumor model; the invention also provides a reagent for the CTC temperature-sensitive bio-gel hanging drop culture method of the liver cancer. Experiments prove that the circulating tumor cells of the liver cancer can be amplified and grown in the temperature-sensitive biological gel system of the invention and become tumor after being inoculated to a nude mouse. The invention provides a model animal for establishing a liver cancer xenograft tumor animal model and individual treatment of liver cancer. |
| priorityDate | 2017-02-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 120.