http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106939031-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_91ba5b549cbd7a36dcf03d0bfbad3dc1 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J71-0005 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-706 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J71-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate | 2017-02-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_187326f3351d886ebe2d95635ddd6307 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_987afc37170b95f7ae81105994713699 |
| publicationDate | 2017-07-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-106939031-A |
| titleOfInvention | A kind of spirosteroid alkane type glycoside alkaloid and its preparation method and application |
| abstract | The present invention provides a spirostanoid alkaloid glycoside alkaloid (3β, 5α, 22α, 25R) - spirostanoid - 3 - O - β - D - glucopyranosyl - (1 → 2) - O - β-D-glucopyranosyl-(1→4)-β-D-galactopyranoside and its preparation method and application, the spirostanoid alkane-type glycoside alkaloid is effective for human lung adenocarcinoma cell A549, human mastocyte Both lung cancer cell H460 and human lung squamous cell carcinoma cell line SK‑MES‑1 have inhibitory effect, and the half inhibitory concentration on A549 cells is 19.22 μg/ml, and the half inhibitory concentration on H460 cells is 80.03 μg/ml, and the half inhibitory concentration on SK‑MES The half-inhibitory concentration of ‑1 cells is 54.20 μg/ml, it can be seen that (3β, 5α, 22α, 25R)-spironalkane-3-O-β-D-glucopyranosyl-(1→ 2)-O-β-D-glucopyranosyl-(1→4)-β-D-galactopyranoside and its preparations can be used to treat non-small cell lung cancer. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111171107-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111440224-A |
| priorityDate | 2017-02-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 61.