http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106924755-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-69 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-337 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5153 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0019 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-05 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-337 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-51 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-69 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-69 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-05 |
| filingDate | 2016-09-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-06-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2020-06-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-106924755-B |
| titleOfInvention | Activated neutral particle cell membrane coated bionic nano particle and preparation method thereof |
| abstract | The invention belongs to the field of pharmaceutical preparations, and relates to activated bionic nanoparticles coated by neutral particle cell membranes and a preparation method thereof. In the invention, the polymer polylactic acid-glycolic acid copolymer PLGA, or polylactic acid copolymer PLA, or polycaprolactone copolymer PCL is used as a material to prepare nanoparticles as an inner core and to encapsulate a model drug, and a natural activated neutral particle cell membrane is used as a capsid to be coated on the surface of the nanoparticles to prepare the biodegradable bionic particle nano-carrier system coated by the activated neutral particle cell membrane. In vivo and in vitro experiments show that the bionic particle nano-carrier system can be used for a bionic treatment system aiming at circulating tumor cells and micrometastasis foci, has the characteristics of strong targeting property and high efficiency, provides a new thought for individuation and accurate treatment, and has higher clinical practice significance. |
| priorityDate | 2015-12-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 160.