http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106905519-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B82Y5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08G2230-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08G64-305 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08G64-081 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1273 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4745 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08G64-0241 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08G64-025 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6835 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-136 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08G64-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-337 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-704 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08G64-183 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6935 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08G64-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-127 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08G64-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-34 |
| filingDate | 2015-12-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2019-07-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2019-07-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-106905519-B |
| titleOfInvention | Biodegradable amphiphilic polymer, polymer vesicles prepared therefrom and application in the preparation of lung cancer targeted therapy drugs |
| abstract | The invention discloses a biodegradable amphiphilic polymer containing disulfide in the side chain, its self-crosslinking polymer vesicle and its application in the targeted therapy of lung cancer. The polymer is obtained by active controllable ring-opening polymerization based on a cyclic carbonate monomer containing a disulfide five-membered ring functional group, the molecular weight is controllable, the molecular weight distribution is narrow, and no protection and deprotection processes are required; The polymer obtained by the ring-opening polymerization of the cyclic carbonate monomer has biodegradability and can be used in a controlled drug release system, and the prepared lung cancer-targeted reduction-sensitive reversibly cross-linked vesicle nano-drug carrier supports stable and long-term circulation in vivo, However, it is highly enriched in lung cancer tissue and efficiently enters cells, rapidly de-crosslinks in cells, releases drugs, efficiently and specifically kills cancer cells, and effectively inhibits tumor growth without causing toxic side effects. |
| priorityDate | 2015-12-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 64.