http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106905431-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-92 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-40 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-13 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P27-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P19-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P19-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P13-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P11-00 |
| filingDate | 2017-04-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-01-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2020-01-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-106905431-B |
| titleOfInvention | Monoclonal antibody against human complement factor D and use thereof |
| abstract | The present invention provides an antibody and an antigen-binding fragment thereof that specifically bind to human factor D with high affinity, a nucleic acid molecule encoding the antibody and the antigen-binding fragment thereof, an expression vector and a host cell for expressing the antibody and the antigen-binding fragment thereof, and a method for producing the antibody and the antigen-binding fragment thereof. In addition, the invention also provides an immunoconjugate comprising the antibody and an antigen-binding fragment thereof, and a pharmaceutical composition thereof, and use of the antibody and the antigen-binding fragment thereof in preparing a medicament for treating various diseases including age-related macular degeneration (AMD), autoimmune diseases, systemic lupus erythematosus, glomerulonephritis, rheumatoid arthritis, and adult respiratory distress syndrome. |
| priorityDate | 2017-04-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 368.