http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106905336-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D491-107 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D491-107 |
| filingDate | 2017-01-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2019-04-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2019-04-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-106905336-B |
| titleOfInvention | A kind of method of asymmetric synthesis of chiral pyrazol spiral shell furfuran compound |
| abstract | The present invention provides the method for asymmetric synthesis of one kind chiral pyrazol spiral shell furfuran compound as shown in formula (I), the synthetic method carries out as follows: will be 1 shown in formula (II), pyrazoles ketene compounds shown in hydroresorcinol class compound and formula (III), chirality side's acid catalyst, organic solvent A mixing, 0.1~48h is reacted at -20~60 DEG C, obtain formula (IV) compound represented, propiodal additive is added into compound shown in formula (IV), alkaline matter and organic solvent B, 0.1~48h is reacted at -20~60 DEG C, reaction solution is post-treated to obtain chiral pyrazol spiral shell furfuran compound shown in formula (I)；Reaction condition of the present invention is mild, and product yield high, selectivity are excellent；The chiral pyrazol spiral shell furfuran compound of preparation has chirality, and core skeleton structure has novelty. |
| priorityDate | 2017-01-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 146.