http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106902098-B
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-416 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L31-042 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-761 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-763 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-768 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0024 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/D04H1-728 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-7007 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L31-148 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L31-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/D04H1-4258 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-768 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/D04H1-4258 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-761 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-763 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L31-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/D04H1-728 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L31-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L31-04 |
filingDate | 2017-02-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2020-07-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2020-07-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-106902098-B |
titleOfInvention | Anti-tumor implant film and preparation method thereof |
abstract | The invention discloses an anti-tumor implant membrane and a preparation method thereof, wherein the anti-tumor implant membrane is an electrospun nanofiber membrane loaded with oncolytic viruses, and the preparation method comprises the following steps: step one, preparing an electrospinning film consisting of nano fibers from a biodegradable high polymer material with amino groups by using an electrostatic spinning technology; and step two, soaking the electrospun nanofiber membrane obtained in the step one into an oncolytic virus solution, and enriching oncolytic viruses on the fiber membrane through electrostatic adsorption to obtain the anti-tumor implant membrane. Aiming at the problems of local chemotherapy, drug resistance and the like after tumor operation and the technical limitation of intratumoral injection when the oncolytic virus is applied, the invention is directly implanted into a tumor resection part to locally treat residual tumor, avoid tumor recurrence and widen the application range of the oncolytic virus. The implant film is made of biodegradable high polymer materials, has good biocompatibility, can be completely absorbed by a human body, can physically isolate a tumor excision part from peritoneum, and plays a role in preventing adhesion. |
priorityDate | 2017-02-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Predicate | Subject |
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isDiscussedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID458396401 |
Total number of triples: 32.