http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106892859-B
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D209-92 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-92 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
filingDate | 2017-03-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2019-06-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2019-06-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-106892859-B |
titleOfInvention | Benzo [c, d] indoles -2 (H) -one-polyamines conjugate and its preparation method and application |
abstract | The present invention relates to a kind of benzo [c, d] indoles -2 (H) -one-polyamines conjugate or its pharmaceutical salts, have the structure as shown in formula I: In formula, m takes 1 or 2;N takes 1,2 or 3;R is 、 、 、 、 、 Or ;X takes 1,2 or 3.The present invention provides benzo [c, d] indoles -2 (H) -one-polyamines conjugate or the preparation methods of its pharmaceutical salts.In addition, it is found through experiment that: aforesaid compound has activity that is good antitumor and inhibiting metastases, and compared with positive control drug ammonia naphthalene Fitow, has higher therapeutic index, there is preparation to prevent and treat the prospect of tumor metastasis medicine;Such compound can be located at cell Asia device lysosome simultaneously, can be used as Cytolysosome targeting fluorescence probe. |
priorityDate | 2017-03-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 42.