http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106884028-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P19-36 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P19-36 |
filingDate | 2015-12-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2020-10-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2020-10-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-106884028-B |
titleOfInvention | Method for enzymatic synthesis of nicotinamide uracil dinucleotide |
abstract | The invention relates to a method for enzymatic synthesis of nicotinamide-uracil dinucleotide and application thereof. Nicotinamide mononucleotide adenosine transferase mutant is used as a catalyst to catalyze the coupling reaction of nicotinamide mononucleotide and uracil nucleoside triphosphate to prepare nicotinamide uracil dinucleotide. The coding gene of the nicotinamide mononucleotide adenyl transferase mutant is expressed in microbial cells, engineering bacteria synthesize nicotinamide uracil dinucleotide with endogenous metabolites, and intracellular nicotinamide uracil dinucleotide can be used as a coenzyme, selectively mediate an oxidation-reduction reaction, and the yield of target metabolites is improved. In a typical example, succinic acid production was increased by 35%. |
priorityDate | 2015-12-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 199.