http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106883321-B
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08B37-0075 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08B37-0003 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08B37-10 |
filingDate | 2017-03-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2019-03-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2019-03-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-106883321-B |
titleOfInvention | A method of extracting Sulodexide bulk pharmaceutical chemicals from heparin sodium by-product |
abstract | The method that the invention discloses a kind of to extract Sulodexide bulk pharmaceutical chemicals from heparin sodium by-product, it is characterized in that by being precipitated after the dissolution of heparin sodium by-product, it is made after collecting sediment through oxidation, precipitating, drying, compared with the prior art, the present invention improves Sulodexide product yield, about 10% is improved than other preparation method yields, cost reduces about 20%.In addition, reducing the power consumption generated using centrifuge the invention avoids the risk for using Benedict's reagent to introduce copper ion pollution.Hydrogen peroxide oxidation step is increased simultaneously; improve product quality; through detecting; 260nm and 280nm absorbance is far below standard requirements; it can be directly used for preparation oral preparation and injection, sample physicochemical property tests and analyzes result and meets enterprise's internal control quality standard, and the present invention is suitable for large-scale production; so that heparin sodium by-product is fully utilized, there are the advantages such as simple technique, energy-saving and environmental protection, with short production cycle. |
priorityDate | 2017-03-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 55.