http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106883266-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C45-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D309-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-6552 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D309-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C49-813 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C45-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-655 |
| filingDate | 2017-01-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-03-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2020-03-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-106883266-B |
| titleOfInvention | Preparation method of 1- (4-chlorphenyl) -2-cyclopropyl-1-acetone and intermediate thereof |
| abstract | The invention relates to a preparation method of 1- (4-chlorphenyl) -2-cyclopropyl-1-acetone, which is prepared from α -hydroxy p-chlorobenzyl phosphonate shown in formula I and 3,4-2 H The preparation method comprises the following steps of (1) -dihydropyran as a raw material, preparing a compound shown in a formula II in the presence of a catalyst, reacting the compound shown in the formula II with cyclopropyl methyl ketone in the presence of alkali and a solvent to obtain a compound shown in a formula III, and hydrolyzing the compound shown in the formula III in an acidic condition to obtain 1- (4-chlorphenyl) -2-cyclopropyl-1-acetone, wherein α -hydroxy p-chlorobenzyl phosphonate and 3, 4-2-propyl phosphonate shown in the formula I H The dihydropyran is used as a raw material, the raw material is cheap and easy to obtain, the steps are simple, the cost is low, the three-waste pollution is less, the environment is protected, the method is suitable for industrial production, and the finally prepared 1- (4-chlorphenyl) -2-cyclopropyl-1-acetone has high purity, the content of more than 96 percent, high yield and the yield of more than 83 percent. |
| priorityDate | 2017-01-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 67.