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classificationCPCAdditional http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2030-8831
classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-88
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-88
filingDate 2017-03-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2018-07-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2018-07-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-106872630-B
titleOfInvention With the screening and application of the relevant biomarker of severe teen bra
abstract The invention discloses a kind of and relevant biomarker of severe teen bra screening techniques, and the mass spectral analysis of depth has been carried out first with the sperm protein undoded amino acid of NanoHPLC MS/MS mass spectrometer systems and label-free proteomics method weak smart disease few to multigroup severe;Then mass spectrometric data is scanned for using non-limiting aminoacid protein modification analysis method, using multivariate Gaussian mixed distribution clustering, largely identifies undoded amino acid in sperm protein group as far as possible;Finally by the comparison of undoded amino acid in normal and patient's sperm protein group, it obtains lacking azoospermia relevant albumen undoded amino acid site with severe, to lack the molecular marker of azoospermia as severe, lacks azoospermia for severe and provide new diagnosing and treating target spot.
priorityDate 2017-03-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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