http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106866799-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2770-24322 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-005 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-18 |
filingDate | 2017-04-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2020-02-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2020-02-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-106866799-B |
titleOfInvention | Hog cholera virus ligand epitope polypeptide SE241 and application thereof |
abstract | The invention discloses a hog cholera virus ligand epitope polypeptide SE241 and application thereof, wherein the amino acid sequence of the polypeptide SE241 is as follows: VHASDERLGPMPCRPKEIGSSAGPVRKTSC are provided. The invention designs and synthesizes a short peptide positioned on the SE24 polypeptide to obtain the polypeptide SE 241. The result of the binding and blocking test of the polypeptide SE241 and PK-15 cells shows that the mean fluorescence intensity of the polypeptide SE241 combined with the PK-15 cells is obviously higher than that of a FITC positive control group, and the mean fluorescence intensity of CSFV blocking the SE241 combined with the PK-15 cells is obviously lower than that of the binding test, so that the polypeptide SE241 can be effectively combined with the PK-15 cells, the combination of the SE241 and the PK-15 cells can be blocked by CSFV, and the SE241 is determined to be a ligand epitope of CSFV combined target cells. Meanwhile, the average fluorescence intensity of the SE241 combined PK-15 cells is higher than that of SE24, the CSFV blocking effect is obviously higher than that of SE24, and the SE241 specificity is better. |
priorityDate | 2017-04-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 87.