http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106866514-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01N43-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C315-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-71 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01P3-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-71 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01N43-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C315-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C317-48 |
| filingDate | 2017-02-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2019-05-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2019-05-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-106866514-B |
| titleOfInvention | A kind of method for synthesizing 2-halogenated-3-substituted hydrocarbyl sulfonyl pyridine and intermediate thereof by aqueous phase method |
| abstract | The invention discloses a method for synthesizing 2-halogenated-3-substituted hydrocarbyl sulfonyl pyridine and an intermediate thereof by an aqueous phase method. The substituted amino acrolein or the substituted cyanoethyl sulfone disappears, and the reaction solution of the 2-halogenated-3-substituted hydrocarbyl sulfonyl pyridine intermediate is obtained; then hydrogen halide is added to the reaction solution to continue the reaction, and the tracking detection is completed until the reaction is complete, and the reaction is sent to the reaction solution. Add alkaline solution to the reaction solution to adjust the pH value to 7-8, stand for stratification to obtain an aqueous layer and an organic layer, extract the aqueous layer with an organic solvent, then combine the organic layers, and then refine to obtain 2-halogenated-3- Substituted hydrocarbylsulfonylpyridines. Synthesis of 2-halogenated-3-substituted hydrocarbyl sulfonyl pyridine by aqueous phase method effectively reduces the use of organic solvents and is beneficial to environmental protection; the reaction time is short and the operation is simple, usually the reaction can be completed within 4 hours, and the product yield is high and the yield is high. The yield can reach more than 90%, which is higher than the yield of the traditional solvent method heating and refluxing. |
| priorityDate | 2017-02-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 232.