| abstract |
The invention discloses a preparation method of a multi-substituted pyridine derivative. The structural formula of the multi-substituted pyridine derivative is: Wherein, X = O or S; R1 is hydrogen , alkyl, aryl or substituted aryl; R2 is phenyl, alkyl, substituted phenyl, pyridine, substituted pyridine, furan, substituted furan, thiophene or substituted thiophene ; R 3 is phenyl, substituted phenyl, pyridine, substituted pyridine, furan, substituted furan, thiophene or substituted thiophene. The invention can synthesize various multi-substituted pyridine derivatives which are not easy to obtain by other methods. |