| abstract |
The present invention relates to natural drugs and medicinal chemistry art, specifically disclose a kind of β elemenes dimer derivate (I), (II), (III) or (IV), wherein X, R 1 、R 2 、R 3 、R 4 、R 5 、R 6 With the same specification of definition of Y.The invention also discloses the preparation method of these β elemene dimer derivates, and the pharmaceutical composition containing the β elemenes dimer derivate or its pharmaceutically acceptable salt and its anti-oxidant aspect application.Pharmaceutical research shows that the derivative of the present invention has the effective antioxidation of low toxicity. |