http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106860447-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-428 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-428 |
| filingDate | 2017-01-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-06-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2020-06-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-106860447-B |
| titleOfInvention | Application of riluzole in inhibiting staphylococcus aureus |
| abstract | The invention discloses application of riluzole in inhibiting staphylococcus aureus, which is used for solving the technical problem that the existing antibiotic drugs have bacterial drug resistance. The technical scheme includes that the riluzole compound is dissolved in an LB liquid culture medium, the riluzole compound is made into uniformly dispersed easy liquid through ultrasound, liquid culture solutions with different drug concentrations are prepared through the LB liquid culture medium through a two-fold dilution method, bacterial suspension is inoculated into the drug culture solutions, the drug culture solutions are cultured in an incubator at 37 ℃ for 18-24 hours, and the lowest bacteriostatic concentration of the riluzole is determined through observing turbidity. Experiments prove that the minimum inhibitory concentration of riluzole is 256 mug/mL-350 mug/mL. The invention provides the bacteriostatic action of the non-antibiotic compound riluzole, provides beneficial help for solving antibiotic drug resistance, and has potential application prospect in the field of medicine. |
| priorityDate | 2017-01-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 68.