http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106831986-B
Outgoing Links
Predicate | Object |
---|---|
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-13 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
filingDate | 2015-12-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2020-01-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2020-01-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-106831986-B |
titleOfInvention | An anti-human HER2 antibody and its encoding gene and application |
abstract | The invention provides an anti-human HER2 antibody, the amino acid sequences of the three hypervariable regions CDRH1, CDRH2 and CDRH3 of the variable region of the heavy chain are respectively: GSISSSNWWS, EIYHSGSTNYNPSLKS, MGANSGGYLYGMDV; The amino acid sequences of the variable regions CDRL1, CDRL2, and CDRL3 are: GLSSGSVSTSYYPS, STNTRSS, VLYMGSGIWV, respectively. The present invention also provides an anti-human HER2 antibody encoding gene and a recombinant plasmid and expression system comprising the encoding gene. The anti-HER2 antibody of the present invention can be used to detect cells expressing HER2, and can also be used to treat human diseases; the fully human anti-HER2 antibody has high affinity, can specifically bind to HER2, and can effectively prevent and treat tumor diseases. |
priorityDate | 2015-12-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 252.