http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106831904-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H15-203 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7034 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H15-203 |
| filingDate | 2017-01-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2019-09-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2019-09-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-106831904-B |
| titleOfInvention | A kind of compound and preparation method thereof, preparation and application |
| abstract | The invention discloses a kind of compound and preparation method thereof, preparation and applications.The structure of the compound is as follows: Wherein: X is halogen, and R is other compounds residues.Preparation method is that Schmidt occurs with four acetyl glucosamine tri- chloroacetimidates as raw material using chloro- 4 hydroxy benzaldehyde of 2- or bromo- 4 hydroxy benzaldehyde of 2- to react, and then is reacted to obtain target compound with NaBH4 or DAST.Preparation is that pharmaceutically acceptable auxiliary material is added in the compound to be prepared into tablet, capsule, injection or freeze drying powder injection.The application in anticoagulation medicine is being prepared using for the compound.Compound of the present invention has apparent blood coagulation resisting function, can be used as potential lead compound, preparation treatment deep vein thrombosis and pulmonary thromboembolism, cardiovascular and cerebrovascular disease, apoplexy and other diseases relevant to blood coagulation drug in use；Preparation method is simple, and favorable reproducibility, environmental pollution is small, can be used for a large amount of preparations of shown compound. |
| priorityDate | 2017-01-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 107.