http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106831711-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-12 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-12 |
| filingDate | 2016-12-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-08-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-08-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-106831711-B |
| titleOfInvention | Benzo [ e ] [1,2,4] triazine-1-oxy derivatives, and compositions and uses thereof |
| abstract | The invention relates to 3- [ (7-chloroquinoline-4-amino) butylamine shown as a formula (1)]-7-substituted-benzo [ e][1,2,4]Triazine-1-oxo derivatives, pharmaceutically acceptable salts, esters, solvates thereof: R 1 selected from hydrogen, hydroxy, C 1 ‑C 6 Alkyl, fluoro, chloro and bromo; r 2 Selected from hydrogen, C 1 ‑C 12 Alkyl or hydroxy; r 3 Selected from hydrogen, C 1 ‑C 12 Alkyl or hydroxy. The invention also provides a composition which comprises the 3- [ (7-chloroquinoline-4-amino) butylamine group shown as the formula (1)]-7-substituted-benzo [ e][1,2,4]Triazine-1-oxo derivatives, pharmaceutically acceptable salts, esters, solvates and pharmaceutically acceptable adjuvants thereof: wherein R is 1 Selected from hydrogen, hydroxy, C 1 ‑C 6 Alkyl, fluoro, chloro or bromo; r 2 Selected from hydrogen, C 1 ‑C 12 Alkyl or hydroxy; r 3 Selected from hydrogen, C 1 ‑C 12 Alkyl or hydroxy. The invention also claims 3- [ (7-chloroquinoline-4-amino) butylamine]-7-substituted-benzo [ e][1,2,4]Triazine-1-oxygen derivatives, and pharmaceutically acceptable salts, esters and solvates thereof are applied to preparation of tumor treatment medicines. |
| priorityDate | 2016-12-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 41.