http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106831349-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C37-055 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C37-74 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C41-01 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C39-27 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C37-055 |
| filingDate | 2017-01-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-07-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2020-07-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-106831349-B |
| titleOfInvention | Preparation method of fluorine-containing phenol |
| abstract | The invention provides a preparation method of phenol containing fluorine, which comprises the following steps: a) mixing a copper catalyst, a ligand, alkali, fluorine-containing bromobenzene and tert-butyl alcohol, and carrying out etherification reaction to obtain fluorine-containing phenyl tert-butyl ether; b) mixing the fluorine-containing phenyl tert-butyl ether obtained in the step a) with concentrated sulfuric acid and water, and carrying out hydrolysis reaction to obtain the fluorine-containing phenol. Compared with the prior art, the preparation method provided by the invention adopts tert-butyl alcohol to directly prepare the fluorine-containing phenyl tert-butyl ether intermediate in a breakthrough manner, and then prepares the fluorine-containing phenol through hydrolysis reaction, the process route is simple, continuous operation can be realized, the reaction condition is mild, the raw material is conventional, the cost is low, and the preparation method is suitable for industrial production; in addition, the preparation method provided by the invention has higher yield, and the prepared fluorine-containing phenol has high purity. Experimental results show that the total yield of the fluorine-containing phenol prepared by the preparation method provided by the invention can reach more than 76%, and the product purity is more than 99%. |
| priorityDate | 2017-01-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 82.