http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106822924-B
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0082 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08G69-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-126 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0054 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-1809 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08G69-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-18 |
filingDate | 2017-02-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2020-06-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2020-06-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-106822924-B |
titleOfInvention | Degradable nano micelle capable of MR-fluorescence bimodal imaging and preparation method and application thereof |
abstract | The invention belongs to the field of nano-medicine and biomedical engineering, and particularly discloses a degradable nano-micelle capable of performing MR-fluorescence bimodal imaging, and a preparation method and application thereof. The nano micelle is based on an amphiphilic block polymer carrier poly (asparaginyl dimethyl ethylenediamine) -cholic acid. The hydrophobic magnetic nanoparticles SPIO and the fluorescent dye nile red are loaded by utilizing the micelle hydrophobic core, so that the neural stem cells can be safely and efficiently marked in vitro, the distribution and migration conditions of the neural stem cells in a living body can be traced in real time after the neural stem cells are transplanted in vivo, the safe and efficient magnetic resonance MR-fluorescence bimodal imaging tracing of the stem cells can be realized, and the application prospect is wide. |
priorityDate | 2017-02-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 51.