http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106822915-B
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-19 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-12 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-61 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-69 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-19 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P19-02 |
filingDate | 2017-01-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2020-04-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2020-04-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-106822915-B |
titleOfInvention | A kind of curcumin hyaluronic acid nanomicelle for treating rheumatoid arthritis and its preparation method and application |
abstract | The invention discloses a curcumin and hyaluronic acid nano-micelle for treating rheumatoid arthritis. The curcumin and hyaluronic acid solution are esterified to form a complex, and self-assembled in the aqueous solution through hydrophilic and hydrophobic forces Nanomicelles are formed; and preparation methods and applications thereof are provided. The beneficial effects of the present invention are as follows: the present invention applies nanotechnology to prepare hyaluronic acid curcumin nanomicelles for the treatment of rheumatoid arthritis, the method is simple to prepare, does not require special equipment, and has low cost; the medicine of the present invention has Good biocompatibility and no toxic side effects in the body; the drug also has obvious joint lubrication and protection, anti-inflammatory and anti-edema effects. After 2 weeks of treatment for rheumatoid arthritis, the swollen joints can be completely restored to their original state, and The joint tissue surface remains normal. Compared with traditional treatment drugs, the drug can greatly shorten the healing period and improve the healing effect. |
priorityDate | 2017-01-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 127.