http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106822915-B

Outgoing Links

Predicate Object
classificationCPCAdditional http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-19
classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-12
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-61
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-69
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-19
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P19-02
filingDate 2017-01-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2020-04-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2020-04-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-106822915-B
titleOfInvention A kind of curcumin hyaluronic acid nanomicelle for treating rheumatoid arthritis and its preparation method and application
abstract The invention discloses a curcumin and hyaluronic acid nano-micelle for treating rheumatoid arthritis. The curcumin and hyaluronic acid solution are esterified to form a complex, and self-assembled in the aqueous solution through hydrophilic and hydrophobic forces Nanomicelles are formed; and preparation methods and applications thereof are provided. The beneficial effects of the present invention are as follows: the present invention applies nanotechnology to prepare hyaluronic acid curcumin nanomicelles for the treatment of rheumatoid arthritis, the method is simple to prepare, does not require special equipment, and has low cost; the medicine of the present invention has Good biocompatibility and no toxic side effects in the body; the drug also has obvious joint lubrication and protection, anti-inflammatory and anti-edema effects. After 2 weeks of treatment for rheumatoid arthritis, the swollen joints can be completely restored to their original state, and The joint tissue surface remains normal. Compared with traditional treatment drugs, the drug can greatly shorten the healing period and improve the healing effect.
priorityDate 2017-01-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

Incoming Links

Predicate Subject
isDiscussedBy http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID61603107
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID415712567
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCA0A6I8S693
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID61480213
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID60667272
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID45957157
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID56731807
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID57990680
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID19225
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID10868
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID61752993
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID969516
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID2875
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID14284
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID49787044
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID442942
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID57975493
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID66671444
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID5280360
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID419537701
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID62225722
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID947
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID45665576
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID450770914
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID282023
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP86348
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID419555718
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID419590658
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID944817
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID469616
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID457569339
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID629
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID1251836
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID60901531
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID22337914
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID57210135
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID13478
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ05700
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID419512635
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID679
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ864W1
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID100135607
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID977
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP04186
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID75205729
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ864W0
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID76282
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ864V9
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID419538066
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID914363
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID1798
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID66939874
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP9WQ91
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID420003593
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ03710
http://rdf.ncbi.nlm.nih.gov/pubchem/anatomy/ANATOMYID10116
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID419556970
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP9WQ90
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID419523291
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP83456
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID6971205
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP19147
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID1024293
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID443460
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP63499
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID55590735
http://rdf.ncbi.nlm.nih.gov/pubchem/taxonomy/TAXID10116
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID100009248
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID100537633
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID61331384
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID29527
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID56963851
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP00634
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID396451
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ05205
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID419547043
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID7962317
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID549559
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID430895435
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID14962
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID2539795
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID24759
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP00751
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID539188
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID180
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID419490115
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID962
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID419524163
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID403086
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID23663392
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID81670
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID5743
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID713
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCO60109
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID57469701
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID60851377
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID45052093
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID61346842
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID30604
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP81800
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID24167418
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID246227
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID56470774
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP21948
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID61614219
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID57243297
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID514076
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID5656924
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID56904445
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID6228
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID294257
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID6800562

Total number of triples: 127.