http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106821986-B
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7088 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K41-0052 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1273 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0019 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0004 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-127 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K41-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7088 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 |
filingDate | 2017-03-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2020-02-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2020-02-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-106821986-B |
titleOfInvention | Gold nanorod-lipid polymer vesicle with transdermal drug delivery function and preparation method and application thereof |
abstract | The invention discloses a gold nanorod-lipid polymer vesicle with a transdermal drug delivery function, and a preparation method and application thereof, wherein the nano vesicle comprises a lipid polymer vesicle and gold nanorods attached in the lipid polymer vesicle, the nano vesicle has good stability, thermal responsiveness and good biocompatibility, the outermost lipid structure can be fused with keratinocytes on the surface of skin and penetrate the skin to enter subcutaneous tumor sites, and the nano vesicle has good gene therapy and thermotherapy effects on melanoma on the surface of the skin and has the advantage of targeted controllable drug delivery. The gold nanorod-lipid polymer vesicle shows a high-efficiency gene therapy effect, so that the gold nanorod-lipid polymer vesicle is very hopeful to be a good carrier for local delivery of gene drugs. The drug-carrying system has wide application prospect in the tumor such as skin melanoma and the like of percutaneous gene therapy. Provides a new research idea and technical reference for the design of a novel gene drug transdermal delivery system in the future. |
priorityDate | 2017-03-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 59.