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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-6486
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-64
filingDate 2017-03-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2019-07-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2019-07-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-106814057-B
titleOfInvention A kind of fluorescence probe, synthetic method and its application being used for Selective recognition ATP based on aggregation inducing fluorescence enhancement characteristic
abstract The invention discloses a kind of fluorescence probe, synthetic method and its applications that Selective recognition ATP is used for based on aggregation inducing fluorescence enhancement characteristic.The present invention synthesizes fluorescence probe 1 by starting material of benzophenone derivates.The present invention has carried out fluorescence probe 1 and has studied the detection of ATP, ADP, AMP and pyrophosphoric acid (PPi), it was found that it has good sensitivity and selectivity to ATP, compared with prior art, the present invention has many advantages, such as that synthesis material is easy to get, fluorescence probe fluorescence quantum yield is high, anti-light bleaching power is strong, avoid the shortcomings that conventional fluorescent dyestuff should not detect in higher concentrations, and the fluorescence probe 1 is used successfully to a kind of reaction process monitoring of ATP hydrolase A pyrase in solution, and is used for the imaging research of intracellular ATP.Therefore, fluorescence probe 1 has great application prospect in terms of detecting internal ATP content.
priorityDate 2017-03-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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