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http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-403
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P33-02
filingDate 2016-12-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2020-02-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2020-02-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-106806366-B
titleOfInvention A new use of isoindole-1,3-dione compounds
abstract The invention provides the application of a novel skeleton compound that can be used as calcineurin kinase in the preparation of medicines for preventing and treating parasitic infections; the isoindole-1,3-dione compounds disclosed in the invention have inhibitory The effect of calcium-dependent protein kinase activity can be used to prepare medicines for preventing or/and treating protozoan infectious diseases, and has potential application prospects in acute and chronic parasitic diseases; through comparative tests, the isoindole-1 of the present invention , the inhibitory activity of 3-diketones against CDPK1 was significantly better than that of pyrazolopyrimidine compounds NM-PP1.
priorityDate 2016-12-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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