http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106801087-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4588f79d8aff5825939c79d0adeb224c |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-686 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6813 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
| filingDate | 2015-11-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_68ec9246303db734691c29bbff5e10b2 |
| publicationDate | 2017-06-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-106801087-A |
| titleOfInvention | CavThe mRNA of 2.1 α 1 are in wild-type mice（n=6）、rolling Nagoya（n=5）With leaner mice（n=5）In expression pattern |
| abstract | The present invention relates to biomedicine field, more particularly to Ca v The mRNA of 2.1 α 1 are in wild-type mice（n=6）、rolling Nagoya（n=5）With leaner mice（n=5）In expression pattern.Cell death and brain damage cause the main cause of ischaemic to be by Ca 2+ What ion-select electrode caused extremely.Two kinds of Ca are used in experiment v The subunit mutant mice of 2.1 channel α 1（Rolling Nagoya and leaner mice）Carry out research Ca v 2.1（P Q types）Physiological action played in ischaemic neuronal damage.Ischemia Experiment result indicates both catastrophic models of rolling Nagoya and leaner mice its brain tissue Embolization areas has obvious reduction compared with wild-type mice.Ca in vitro 2+ In the research of imaging, two kinds of Ca v The Ca of 2.1 passage mutant mices 2+ The comparing of getting up compared with wild-type mice of the growth rate of concentration is slow.These results of study indicate Ca v 2.1 passages are in Ca 2+ Played an important role in the ischaemic model of dependence, if blocking this passage can play certain prevention and protective effect. |
| priorityDate | 2015-11-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 27.