http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106801043-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P13-001 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y206-01 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-1096 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-04 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-19 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P13-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-54 |
| filingDate | 2016-12-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2019-08-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2019-08-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-106801043-B |
| titleOfInvention | A kind of recombination transaminase and its preparation method and application |
| abstract | The invention discloses a kind of recombination transaminases and its preparation method and application.A kind of recombination transaminase mutant of high activity, amino acid sequence is as shown in SEQ ID NO.2, and encoding gene is as shown in SEQ ID NO.1.A method of the recombination transaminase is prepared, the genetic engineering bacterium of above-mentioned encoding gene is contained including fermented and cultured, and collect and preparation and reorganization transaminase.Recombination transaminase of the present invention is applied to asymmetric syntheses chirality aminated compounds, especially for synthesizing sitagliptin intermediate (R) -3- amino -4- (2,4,5- trifluorophenyl)-methyl butyrate.Enzyme according to the present invention has excellent stereoselectivity, regioselectivity and catalysis activity, and the reaction of its catalysis is mild, and the yield of reaction conversion ratio and product is high, with good application prospect. |
| priorityDate | 2016-12-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 462.