abstract |
The present invention relates to a kind of disubstituted aryl class compound and its applications, the disubstituted aryl class compound structure is as shown in Formulas I, II or III, find that such disubstituted aryl class compound can be used in conjunction with triazole antifungal agent object by experimental verification, drug-fast bacteria can be improved to the sensibility of azole drug, realize reversing drug resistance, therefore the present invention provides a kind of new way for the treatment of clinical drug-resistant fungi. |