http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106795174-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-537 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D498-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D241-08 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D241-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-537 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D498-20 |
filingDate | 2016-08-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2020-04-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2020-04-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-106795174-B |
titleOfInvention | Antiviral active diazacyclospirodiketopiperazine alkaloid derivative and preparation method thereof |
abstract | The invention relates to an antiviral active diazacyclospirodione piperazine alkaloid derivative and a preparation method thereof, in particular to anti-RSV, HSV-1 and EV71 activities of a compound shown in a formula I, wherein the compound shown in the formula I has the following structure: wherein R is 1 、R 2 、R 3 、R 4 Each independently selected from the group consisting of optionally substituted H, alkyl, cycloalkyl, alkylacyl, alkoxyacyl, cycloalkylacyl, alkenyl, alkenylacyl, alkynyl, alkynylacyl, aryl, arylalkyl, arylacyl, heteroaryl, heteroarylalkyl, heteroarylacyl, saturated or unsaturated heterocyclyl, saturated or unsaturated heterocyclylalkyl, saturated or unsaturated heterocyclylacyl; n is 0 or 1; chemical bond(s) Indicating keys pointing into the surface of the paper Or keys pointing out of the plane of the paper "- - - - -" represents a single bond or is absent, and when "- - - -" represents a single bond,R 1 、R 2 is absent. |
priorityDate | 2015-08-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 339.