| abstract |
Provided are methods and compositions for eliciting an immune response to Group A Streptococcus bacteria in a mammal, comprising administering to the mammal a fragment of the M protein, a variant or derivative thereof and a SpyCEP protein or peptide fragment, or directed against all Antibodies to SpyCEP proteins or fragments described above to promote recovery or enhance neutrophil activity. Immunodominant peptide fragments of SpyCEP are also provided. |