| abstract |
Provided herein are placental extracellular matrix (ECM) compositions and methods for their preparation. Also provided herein are uses of the placental ECM compositions provided herein. In one aspect, provided herein are extracellular matrix (ECM) compositions prepared using placental tissue, such as human placental tissue. In certain embodiments, the ECM compositions provided herein comprise from about 30 to about 60% collagen and from about 10 to about 35% elastin. Additionally, such ECM compositions comprise (i) very low amounts of fibronectin (e.g., less than 0.1% fibronectin), e.g., as measured by ELISA; (ii) no or undetectable amounts of laminin , for example, as measured by ELISA; and/or no or undetectable amounts of glycosaminoglycans. |