| abstract |
Paper-based microfluidic chip for detection of hemoglobin in whole blood and its production and application, processing cytoplasm pre-separation, blood cell elution, cell lysis and hemoglobin release, interfering impurities removal, Multiple functional units such as a three-level system; fan-shaped elution pools containing laser-etched array micro-slits of different densities, used for multiple rapid washings of blood cells and hemoglobin with different eluents; simple physical modification by methylene blue The polished carbon working electrode accelerates the electron transfer between hemoglobin and the electrode, so that the three-electrode system has a larger current response and detection range; by simply stacking and partially folding the functional units in different regions of the chip, you can obtain Three-dimensional paper-based microfluidic chip with three-dimensional structure; the whole detection process is simple to operate, fast in analysis speed, and requires a small sample volume, suitable for rapid detection of hemoglobin content in whole blood in home medical care, field emergency, remote and underdeveloped areas, etc. . |