abstract |
The invention belongs to genetic engineering field, in particular to application of the PVT1 in preparation diagnosis preeclampsia and target drug treatment;The downward of PVT1 is related with the occurrence and development of preeclampsia in preeclampsia pregnant women placental tissue, the PVT1 and Attack of Preeclampsia mechanism of low expression level have close relationship, expression by changing PVT1 has an impact the proliferation of preeclampsia pregnant woman's trophocyte, apoptosis, invasion, migration etc., and enhancing PVT1 expression can promote trophoblastic proliferation, invasion and migration. |