http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106753337-B

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filingDate 2016-12-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2018-06-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2018-06-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-106753337-B
titleOfInvention A kind of near-infrared and two-photon Double-mode imaging fluorescence probe and its preparation and application
abstract The present invention relates to the preparations and application of a kind of near-infrared and two-photon Double-mode imaging fluorescence probe, belong to chemical biology technical field.The near-infrared and two-photon Double-mode imaging fluorescence probe of the present invention is using Nile red derivative and biotin as Material synthesis, is a kind of brown product.The fluorescence probe of the present invention has good spectral quality, respectively by the use of 540nm and 590nm as excitation wavelength, occurs maximum emission wavelength at 660nm, and fluorescence intensity is higher.The fluorescence probe of the present invention, also has targeting to tumour cell, is a kind of targeting near infrared fluorescent probe;On the one hand it can be realized under the premise of tissue sample is not destroyed and detect internal signal in real time;On the other hand the enrichment of signal within the tumor can be improved, improves signal-to-noise ratio.The fluorescence probe of the present invention can both carry out near infrared imaging, while can also carry out two photon imaging, and both of which is mutually authenticated, and can improve the accuracy of result.
priorityDate 2016-12-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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