http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106750254-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08G65-3348 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4745 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4745 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08G65-334 |
| filingDate | 2017-01-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2019-05-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2019-05-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-106750254-B |
| titleOfInvention | pH-sensitively released 10-hydroxycamptothecin water-soluble macromolecular conjugate and preparation method and application |
| abstract | The invention discloses a pH-sensitively released 10-hydroxycamptothecin water-soluble macromolecule conjugate and a preparation method and application thereof. Through structural modification, the conjugate greatly improves the water solubility of 10-HCPT; improves the pharmacokinetic properties of 10-HCPT; utilizes the characteristics of tumor microenvironment to achieve pH-responsive drug release with controlled release effect; Chemical bond drug loading, high drug loading capacity, no drug leakage; chemotherapeutic drugs can be targeted to tumors and stay for a long time, with good targeting. |
| priorityDate | 2017-01-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 27.