http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106749464-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J5-0076 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J7-0055 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J7-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J5-00 |
| filingDate | 2016-12-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2019-01-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2019-01-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-106749464-B |
| titleOfInvention | Steroidal epoxide carries out the method and device thereof of open loop, fluorination reaction |
| abstract | The invention discloses the methods of prepare compound II a kind of, as shown in following reaction equation: In the solvent that aromatic hydrocarbons and water form, hydrogen fluoride is fluorination reagent, and steroidal epoxide I carries out the open loop of epoxide, fluorination reaction, prepares the fluoro- 11 beta-hydroxy steroidal compounds II of 9 α-, in above formula: R CH 3 、CH 2 OH or CH 2 OAc；R 1 For OH；R 2 For α-CH 3 Or β-CH 3 ；R 3 For F or H.Continuous reacting device as shown in Figure 1 can be used in the method for the present invention. |
| priorityDate | 2016-12-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 25.