abstract |
The present invention relates to a class of substituted triazolopiperazine compounds represented by the following general formula (I), their tautomers, enantiomers, diastereomers, racemates, metabolites, and metabolic precursors And pharmaceutically acceptable salts, esters, prodrugs or hydrates thereof, preparation methods thereof, intermediates and uses thereof in the preparation of drugs for the prevention and treatment of PARP-related diseases, which include various ischemia diseases, neurodegenerative diseases and cancer. |