http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106749210-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D409-06 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P17-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D409-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P19-02 |
| filingDate | 2016-11-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2019-08-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2019-08-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-106749210-B |
| titleOfInvention | A kind of nicotinate compound and the preparation method and application thereof |
| abstract | The present invention relates to a kind of nicotinate compounds and the preparation method and application thereof, the compound is 2- hydroxyl -3- (capric acid aliphatic radical) -6- (4,4 '-dimethyl-thiochroman base -6- acetenyl) nicotinate, condensation reaction is carried out with 2- hydroxyl -3- (capric acid aliphatic radical) alcohol with 2- hydroxyl -3- (capric acid aliphatic radical) -6- (4,4 '-dimethyl-thiochroman base -6- acetenyl) niacin application dicyclohexylcarbodiimide (DCC) to obtain；It is to prepare two kinds of Retinoic acid receptor (RAR- β of selective binding；RAR- γ), but the important intermediate for the drug not combined with Tretinoin X receptor (RXR), it is to prevent and treat psoriasis arthropathica, psoriasis arthropathica, the key components of psoriatic arthritis drug；Preparation method raw material is cheap and easily-available, and synthetic method is simple, is a kind of completely new approach for synthesizing nicotinate compound, is suitble to the needs of scale industrial production. |
| priorityDate | 2016-11-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 26.