http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106748988-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_653c418e41edbb4e1ce8bc5e53e70cec |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C315-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-71 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C317-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-71 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C315-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01P3-00 |
| filingDate | 2017-02-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7385d026cef7e92ccda77e028914faa1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dc42d0d65c08eb2e24b56988632fbe7b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_badc46cc1cc4780ec8f216f998de51bf http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_19ecc1f93cbdcbd2b487aa05c8cb7680 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_566d04d8405c36bdb4fd34f56bbf74f1 |
| publicationDate | 2017-05-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-106748988-A |
| titleOfInvention | A method for synthesizing 2-halo-3-substituted hydrocarbylsulfonylpyridines and intermediates thereof by ultrasonic method |
| abstract | The invention discloses a method for synthesizing 2-halo-3-substituted hydrocarbylsulfonylpyridine and its intermediates by ultrasonic method, in which aminoacrolein, catalyst and substituent cyanoethyl sulfone are reacted to complete reaction under ultrasonic to prepare Obtain the reaction liquid of 2-halo-3-substituted hydrocarbylsulfonylpyridine intermediate; add hydrogen halide to the reaction liquid at a certain temperature to continue the reaction until the reaction is complete, add lye to the reaction liquid to adjust the pH value to 7-8, The water layer and the organic layer were obtained by static layering, the water layer was extracted with an organic solvent, and then the organic layers were combined and refined to obtain 2-halo-3-substituted hydrocarbylsulfonylpyridines. Synthesis of 2-halo-3-substituted hydrocarbylsulfonylpyridines by ultrasonic method can effectively promote organic synthesis reactions, speed up the reaction speed and increase the reaction yield, which is beneficial to environmental protection; the reaction time is short and the operation is simple, usually within 2 hours. The reaction is completed, the product yield is high, the quality is good, and the yield can reach more than 90%, which is higher than the yield of the traditional solvent heating reflux method. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108329237-A |
| priorityDate | 2017-02-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 24.