http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106748859-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C231-12 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C237-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C231-12 |
| filingDate | 2016-10-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2018-10-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2018-10-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-106748859-B |
| titleOfInvention | A kind of preparation method of Ioversol |
| abstract | The present invention provides a kind of preparation methods of Ioversol.Specifically, this method includes (1) 5- chloro acetylaminos-N, N'Alkylated reaction occurs under alkaline condition for double-(2,3- dihydroxypropyl) -2,4,6- tri- iodo- 1,3- benzenedicarboxamides and chlorethanol, and (2) are made by sodium acetate hydrolysis.Aforementioned two-step reaction uses the container that anti-corrosion layer is coated on inner wall, the use of iron content is 0.05ppm water below.This method can effectively avoid the generation of troublesome impurity, be suitable for industrialized production. |
| priorityDate | 2016-10-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 52.