http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106748695-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C45-74 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C45-74 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C47-24 |
| filingDate | 2016-11-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-09-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2020-09-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-106748695-B |
| titleOfInvention | Preparation method of m-trifluoromethyl cinnamaldehyde |
| abstract | The invention discloses a preparation method of m-trifluoromethyl cinnamaldehyde, which is prepared by one-step aldol condensation reaction of m-trifluoromethyl benzaldehyde and acetaldehyde in the presence of an alkaline catalyst; wherein the basic catalyst is DBU, triethylamine or diisopropylethylamine, and the molar ratio of DBU to m-trifluoromethylbenzaldehyde is 1: 10-3: 5; the molar ratio of acetaldehyde to m-trifluoromethylbenzaldehyde is 1: 1-5: 1; the condensation reaction is carried out in the presence of methanol, methyl tert-butyl ether or tetrahydrofuran. The method has the advantages of short synthetic route, mild reaction conditions and simple operation, and particularly, a product with the purity of more than 98 percent can be obtained with better yield by selecting a proper alkaline catalyst, so that the method is suitable for large-scale industrial production and has higher application value. |
| priorityDate | 2016-11-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 45.