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filingDate 2016-12-31-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2019-07-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2019-07-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-106729976-B
titleOfInvention A kind of PELCL/ polycaprolactone-REDV electrospun fiber membrane and preparation method
abstract The present invention relates to a kind of poly- (L- lactide-co- 6-caprolactone)/poly-epsilon-caprolactone-REDV of polyethylene glycol-b-, and ultra-fine electrospun fiber membrane and preparation method is blended.REDV small peptide is coupled with low molecular weight poly-epsilon-caprolactone, prepare poly-epsilon-caprolactone-g-REDV, and it is dissolved in chloroform and N together with high molecular weight polyethylene glycol-b- poly- (L- lactide-co- 6-caprolactone), in the mixing solvent of dinethylformamide, superfine fibre film is prepared by electrospinning method.The electrospun fiber membrane is made of the superfine fibre that diameter is 400~1000nm, with a thickness of 50~200 μm.REDV small peptide is contained on electric-woven super-fine fiber film of the invention, surface, has the function of promoting vascular endothelial cell adherency and growth;Superfine fibre film has the ability of control release of bioactive substances for containing the bioactive substances such as nucleic acid, albumen, drug simultaneously.For bio-medical material.
priorityDate 2016-12-31-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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