http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106729749-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4184 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4745 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-87 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P11-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4745 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4184 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-69 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-87 |
| filingDate | 2017-02-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2019-11-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2019-11-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-106729749-B |
| titleOfInvention | It is a kind of to can be realized the transmission system and the preparation method and application thereof that gene and drug carry altogether |
| abstract | It can be realized the transmission system and the preparation method and application thereof that gene and drug carry altogether the invention discloses a kind of, belong to nano-drug preparation technical field.It is described to can be realized cationic pharmacome that the transmission system that gene and drug carry altogether is self-assembly of by environmental response type lipid prodrug and gene is compound constitutes.The lipid prodrug is keyed hydrophilic resin shape molecule head and hydrophobic anticancer drug by environment sensitive or its prodrug is constituted.The environment sensitive key can be broken under specific environmental condition, separate the hydrophobic anticancer drug or its prodrug with hydrophily dendrimer, make the cationic pharmacome that de-assembly occur and discharge gene.The pharmacome is while improving encapsulation rate and drugloading rate, additionally it is possible to compress gene and form total transmission delivery system.It can be realized gene and drug synergistic treatment or sequential therapeutical effect. |
| priorityDate | 2017-01-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 57.