http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106728436-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_da2f79017444789d747982d4ab13b908 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2236-55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2236-333 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2236-51 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2236-39 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K36-85 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P1-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K36-85 |
| filingDate | 2016-12-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2c69311c6b8426dbba6bb53ef4f5221a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_80d5bbec9973555c923be07f76231a36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_22b6cd9ef2cd4f9105c6b18115538776 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_09dbbd1ed8f84541eb17000bf767ef75 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_35d5c1299e7d3c071e843c80eac2dd19 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fe9f26685bd706dd09cda5cf939a4eee |
| publicationDate | 2017-05-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-106728436-A |
| titleOfInvention | Extraction method of total flavonoids from Guoqiangfeng and its application in the preparation of hepatoprotective drugs |
| abstract | The invention discloses a method for extracting total flavonoids from cross-wall wind and its application in the preparation of liver-protecting medicines. Taking ethanol concentration, extraction temperature, and extraction time as independent variables, and the yield of total flavonoids as dependent variables, a star point design-effect The surface method was used to optimize the extraction process of total flavonoids from the wall wind, and the optimal process conditions were: ethanol concentration 54.76%, extraction temperature 83.92 °C, extraction time 102.64 min, solid-liquid ratio 1:20, extraction twice, under these conditions highest rate. The extraction process is simple and feasible, the prediction result is reliable, and it is suitable for industrial production. In addition, the total flavonoids of crossing the wall wind acted on the liver injury model of carbon tetrachloride to test the hepatoprotective effect. The experimental results showed that the total flavonoids of the crossing the wall wind had the effect of protecting the liver, and the mechanism of action may be caused by TNF‑α, IL‑6 Hepatocyte inflammatory response mediated by NO and NO can effectively protect liver cells. |
| priorityDate | 2016-12-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 88.