http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106727723-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-65 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-65 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate | 2016-12-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-07-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2020-07-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-106727723-B |
| titleOfInvention | Method for removing irritant substances in venenum bufonis medicinal materials |
| abstract | The invention discloses a method for removing irritative substances in toad venom, which comprises the steps of mixing toad venom medicine powder with water according to a certain proportion, extracting for a period of time, standing, carrying out liquid-solid separation, and removing supernatant fluid to obtain the toad venom medicinal material from which the irritative substances in the toad venom medicinal material are removed. By combining pharmacological experiments with chemical analysis means and adopting a large number of experimental screening processes, the method can obviously reduce the irritative substances such as polypeptide, tryptamine and the like in the toad venom, so that the irritative substances of the medicinal material toad venom are obviously reduced, but the antitumor active ingredients are well reserved, and the antitumor activity is not influenced. The method provided by the invention has reasonable process design and strong operability, can effectively remove irritative substances of the venenum bufonis medicinal material, reduce the irritative property of the venenum bufonis, does not reduce the anti-tumor effect of the venenum bufonis medicinal material, and can provide safety guarantee for the clinical application of the venenum bufonis medicinal material. |
| priorityDate | 2016-12-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 17.